Synthesis of novel sulfonamide derivatives containing phthalimide moiety | ASJP

Synthèse
Volume 28, Numéro 1, Pages 8-12
2022-09-11

Synthesis Of Novel Sulfonamide Derivatives Containing Phthalimide Moiety

Authors : Redjemia Rayenne . Boussaker Meriem . Bahadi Rania . Berredjem Malika .

Abstract

An efficient and eco-friendly green methodology is developed for the synthesis of novel sulfonamide derivatives from sulfanilamide and phthalic anhydride in ethanol as solvent, using ultrasound irradiations. High yield, short reaction time, green conditions and optimization with the design of experiment are the major advantages of this method. The structures of the synthesized compounds were carefully characterized by 1H, 13C NMR as well as IR.

Keywords

sulfonamide ; sulfanilamide ; phthalic anhydride ; ultrasound irradiation

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