Revue des Sciences Fondamentales Appliquées
Volume 6, Numéro 1, Pages 106-115107
2014-01-01

Thermodynamic Parameters Of Solutions Of Sildenafil Citrate In Some Organic Solvents At Different Temperatures



Authors : Baluja S. . Bhesaniya K. .

Abstract

The solubility of Sildenafilcitrate in someorganic solvents; hexane, toluene,1-butanol and 1,2 dichloroethanehas been determined using gravimetric method over different temperature range (298.15 K to 328.15 K) at one atmospheric pressure. The modified Apelblat and Buchowski-Ksiazczak λh equations were used to correlate the experimental solubility data.Further, various thermodynamic parameters have been evaluated from these solubility data.

Keywords

Solubility, Organic solvents, Sildenafil citrate, Thermodynamic parameters

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