Can ADVIA 2120i replace blood smear ?

Bennaoum, Mohammed Nazim; Lazreg, Hassiba; Bechir, Fatima; Bedjaoui, Fatima Zohra; Hammadi, Mohamed

Batna Journal of Medical Sciences
Volume 3, Numéro 1, Pages 15-17
2016-06-29

Can Advia 2120i Replace Blood Smear ?

Authors : Bennaoum Mohammed Nazim . Lazreg Hassiba . Bechir Fatima . Bedjaoui Fatima Zohra . Hammadi Mohamed .

Abstract

Introduction. The ADVIA 2120i is one of the most efficient analyzers used in hematology laboratories. In addition to the quantification of cells; it enables the detection of cytological abnormalities and alert biologist by specific alarms. Material and methods. We conducted a prospective study in the EHU Oran for 3 months. Overall, 146 blood samples were analyzed for which the analyzer reported various cytological alarms and we reviewed them under the microscope as a gold standard. Results. This study allowed us to determine how the ADVIA 2120i can be helpful for routine use in screening cytological abnormalities. According to our results, it turned out that the analyzer is efficient for erythrocyte morphological abnormalities such as microcytosis, macrocytosis, hypochromy, and anisocytosis. However, concerning leukocytes; we found a high rate of false-positive cases, the specificity should be improved especially for detection of blasts.